Friday, January 31, 2020
Avian Flu Virus Essay Example | Topics and Well Written Essays - 2000 words
Avian Flu Virus - Essay Example Moreover, it has been known that this H5N1 virus is able to infect other animals other than birds and pigs, such as, cats and larger felines, and transmission of infection from other animals to human may occur unknowingly. An article published in the Journal of Virology in the year 2005, titled "Avian Influenza (H5N1) Viruses Isolated from Humans in Asia in 2004 Exhibit Increased Virulence in Mammals" and researched by Maines and co-workers investigates this in an isolate of the virus of the H5N1 strain, isolated from 2004 Asian epidemic, and in this work, that article will be critiqued. Research Questions: As is apparent from the epidemiologic patterns of the outbreak of these H5N1 infections, the virulence factors responsible for human disease need to be elucidated. The problem remains that the virulence factors of H5N1 viruses is poorly understood from the biologic and molecular perspectives, this being an avian virus transmitted to humans. It points to the need for mammalian models of studies, and since there is evidence that mammalian experiments in nonhuman primates such as ferrets and mice have been studied for influenza virus pathogenesis and other nonhuman mammals may also serve as carriers for human virus, nonhuman primate studies may serve as an acceptable model. In these models, the relative virulence of the H5N1 isolated from 2003-2004 outbreaks in both humans and avian species can be studied, and the authors can have the advantage of comparing them with earlier 1997 H5N1 human isolates to compare the virulence of the virus, so a molecular or biologic c orrelate is available that may be applied in the management of human epidemics. Relevance of the Question: From the public health point of view, the circulation of H5N1 virus in the poultry may cause more human cases with human-avian reassortant pandemics. Epidemiologic observations have demonstrated that from the time of first recognition and isolation, the virulence of this strain is increasing markedly over the years in terms of mortality and case fatality rates. Although the clinical presentations of the human cases were usual in the form of fever, respiratory symptoms, diarrhea, lymphopenia, and thrombocytopenia, in rare occasions, they indeed presented with just fever and gastrointestinal symptoms. This could have indicated a change in the pattern of virulence, despite the pattern of fatality remaining the same, that is, development of pneumonia with critical compromise in gas exchange, leading to respiratory failure and death despite assisted ventilations. Research in this area is necessary since there is a paucity of research answering this question abou t how an infection with this virus leads to acute respiratory distress and multiple organ dysfunctions in humans. Although studies in mammalian models do have constraints from the practical, ethical, and economic perspectives, it could be a valid option since ferret is a naturally susceptible host to influenza A virus, has been used in previous studies to evaluate H5N1 virulence and safety and efficacy of vaccine candidate preparations. Moreover, the same authors previously studied H5N1 virus virulence in ferrets and they have valid criteria for assessment, where they demonstrated earlier equivalence in
Thursday, January 23, 2020
Frogs :: essays research papers
Frogs à à à à à Frog is the common name for a species of amphibian that also includes toads. A very common question is ââ¬Å"whats the difference between frogs and toads?â⬠, the answer: none, except for the fact that toads lack the powerful legs that frogs have. ââ¬Å"Where can frogs and toads be found?â⬠, one might ask. They live in all parts of the world, except for Antarctica, but are mostly found in tropical areas. Frogs are small animals with smooth moist skin, and big eyes that can see in almost any direction. Most species have webbed feet and powerful legs making them good jumpers, and excellent swimmers. A frogs tongue is attached to the front of itââ¬â¢s mouth instead of the rear, and most frogs are very vocal, especially the male frogs. à à à à à As a frog grow, it goes through many changes. Starting out as a tadpole, and morphing into a frog. Most frogs lay their eggs in water. Others will lay their eggs some where safe, then carry them to water where they hatch into tadpoles. At this stage they have gills, no legs, and a tail. As they mature, their gills and tail disappear, and they develop lungs and legs. This period of tadpole life can be divided into three stages. The first stage, called ââ¬Å" premetamorphosis,â⬠lasts about 50 days (Patent 54). The second stage, in which the hind legs grow, is called ââ¬Å"prometamorphosis,â⬠and lasts about 21 days. When the legs are about as long as the body, the third stage, which is called ââ¬Å" metamorphic climax,â⬠and takes place very rapidly, begins. During this last stage, which lasts about a week, many great changes occur. They lungs complete their development, and the gills disappear. The skin gets thicker, nostrils form, and the tail is completely resorbed. à à à à à Most frogs prefer moist regions, and many kinds live in the water. Because frogs absorb oxygen in water through their skin, they can stay underwater for long periods of time. A frogs body temperature depends on itââ¬â¢s surroundings, and during cold weather, frogs dig burrows in mud and hibernate. During hibernation, the frog needs little oxygen and no more food than is already in itââ¬â¢s tissues. During intense heat, a frog might estivate, or in other words, lie in a state of torpor during the heat, after burying themselves in sand and clay. à à à à à Frogs are carnivores. They eat just about anything smaller than then that moves. A frog thinks like this: If itââ¬â¢s smaller than itself and moves, eat it. If itââ¬â¢s the same size, mate, or attempt to mate (this gets some frogs
Wednesday, January 15, 2020
Philosophies & Democracy Essay
Democracy and capitalism gave way to concentration of wealth amongst a small group of people. Private entrepreneurship got a boost due to capitalism. Given this scenario, many private entrepreneurs rose to build their industrial empires. There are many examples, where, the starting point of a given business was zero, and it rose to become a leading international business house. Increase in business, resulted in exaggerated accumulation of wealth in the hands of a few, and that was the time, when these new class of rich entrepreneurs, gave a thought to the society, in which they have been operating, and which has supported their enterprise in its rise. Carnegie Melon, at the beginning of industrial revolution, and Bill Gates, at the end of the twentieth century, are two solid examples of business rise from zero to international giants. Both of them, spent their full life, in amassing wealth, and as they grew, they started framing corporate philosophies, which put society at the focus of their activities. While they applied the rule of ââ¬Ëeverything is fair in businessââ¬â¢, they turned towards society at the fag end of their lives. Corporate philosophies, by and large have nothing new to say, except that they work for the society, and they care for their customers. All corporate philosophies are concentrated around these central themes, in different words and sentences. Often, it is proved that corporate philosophies are not as sweet as they sound. When it comes to business, these philosophies are sacrificed, partially or fully. Was only genuine software skill responsible for the stupendous rise of Bill Gates and Microsoft? Of course no. There is in fact, considerable shrewdness going into the rise of Microsoft. In fact, corporate houses, as they grow, turn their attention towards betterment of society, in one or the other way. There are numerous examples to prove this, in the time gap between Carnegie Melon and Bill Gates. However, they are targeted at multiplication of business. An average American fully understands the implications of these corporate philosophies, and their implied meanings. For example, when cyber attacks started assuming alarming proportions, Bill Gates ordered a change in their corporate philosophy. It implied change in the approach of all software development. Now, instead of adding new features to the software, the focus was to be laid on protection of the software, because, Bill Gates argued, ââ¬Å"In the past, weââ¬â¢ve made our software and services more compelling for users by adding new features and functionality, and by making our platform richly extensible . . . but all those great features wonââ¬â¢t matter unless customers trust our software,â⬠wrote Gates. ââ¬Å"So now, when we face a choice between adding features and resolving security issues, we need to choose security. â⬠( Trustworthy computing, para 2) ââ¬Å"Some of Microsoftââ¬â¢s perennial critics claim the initiative is long overdue, and question whether or not Microsoft will follow through on its promises, as the company could be forced to bear a reduction in the number of new features in its programs and significant new product delays. Some go further in arguing that such a massive security initiative cannot be undertaken without subjecting the Windows operating system source code to public domain ââ¬â something the company has fought hard to avoidâ⬠. Writes an observer, in his opinion. ( Trustworthy computing, Para 4) What is true of Microsoft , is perhaps true of other companies also. An average American is well aware of the status of the company, and its capacity to deliver the promised goods, and is also right in judging the ethical behavior of a company. Conclusively it can be said that despite the tall claims made by the corporate philosophies, the average American of the ins and outs of that firm. References: 1) Trustworthy computing, Security and privacy deemed Microsoftââ¬â¢s top priorities, retrieved on 5 May 2009 from :
Tuesday, January 7, 2020
Factors Influencing Individual Investor Behavior - 1439 Words
Factors Influencing Individual Investor Behavior: An Empirical study of the KSA Financial Market research Contents TITLE PAGE NO 1. ABSTRACT 3 2.INTRODUCTION 2.1 Background to the Study 2.2 Statement of The Problem - Specific Objectives of the study - Research Questions 2.3 The scope of the study 2.4 The Relevance of the study 4 5 6 6 7 7 3. LITERATURE REVIEW 8 4. THE RESEARCH DESIGN a. Type of study b. the Model equation c. Hypothesis d. Data collection methods c. The sapling design f. Statistical analysis technique 10 10 10 10 10 11 5. INTERPRETATION OF RESULTS 11 6. SUMMARY AND CONCLUSIONS 12 TIME FRAME 13 REFERENCES 14 2.4The Relevance of the study This study aims at exploring the KSA investorââ¬â¢s behavior, appearâ⬠¦show more contentâ⬠¦The results indicate; by using Regression Analysis, that the most influencing factor in order of importance are expected corporate earnings, get-rich-quick, stock marketability, past performance of the firmââ¬â¢s stock, government holdings and the creation of the organized financial markets. Al- Owaisi (2010) study examines the factors influencing the investment behavior of individual investors at Palestine Securities Exchange in Gaza strip. Some of these factors include stability of investing environment, performance of registered companies at Palestine Securities Exchange and performance the level of the exchange market itself. The study uses a descriptive analytical method based on data gathering and analysis. The number of returned questionnaires 274. The study revealed that many investors cared about following the latest developments of exchange market and other businesses through mass media. It also found that staffs of financial mediators working at Palestine Securities Exchange are not fully competent to help investors take their own investment decisions. Furthermore, rumors constitute a major external factor negatively affecting investment. The study also showed that the possibility of investment aboard has a negative impact on investment decisions in the Palest ine Securities Exchange. MerikasShow MoreRelatedThe Costs And Benefits Of Financial Advice Essay1191 Words à |à 5 PagesBrian Melzer, Alessandro Previtero. This thesis assesses the value that financial advisors provide to clients using a unique panel datasheet on the Canadian financial advisory industry. 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Department of Business Management Fakir Mohan University, Vyasa Vihar-756019, Balasore, Orissa, India Tel: 91-94371-31429 E-mail: bhagaban_fm@yahoo.co.in Ms. Sangeeta Mohanty Associate Professor, Academy of Business Administration Industrial Estate (S1/25), Angaragadia, Balasore ââ¬â 756001, Orissa, India E-mail: sangeeta_mohanty@rediffmail
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